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GCE CIE BIOL - Collagen (Fibrous Proteins) 

Chapter 2 Biological Molecules

· biology,gce cie,collagen,fibrous,protein

2.3.c Describe the molecular structure of haemoglobin as an example of a globular protein, and of collagen as an example of a fibrous protein and relate these structures to their functions (The importance of iron in the haemoglobin molecule should be emphasised. A haemoglobin molecule is composed of two alpha (α) chains and two beta (β) chains, although when describing the chains the terms α-globin and β-globin may be used. There should be a distinction between collagen molecules and collagen fibres).

  • Fibrous proteins are present in the skin, bones, teeth, cartilage and walls of blood vessels. 
  • It is an important structural protein.
General structure of a fibrous protein.

The above image shows the structure of a fibrous protein. 

COLLAGEN

  •  Collagen has a structure with three polypeptide chains that are held together by hydrogen and covalent bonds. 
  • Each polypeptide chain are wound around each other, in a triple helix (or like a rope). 
  • Every third amino acid is a glycine.
  • Collagen molecules linked to each other by cross-links between side chains of amino acids, which forms fibrils.
  • Groups of fibrils make up collagen fibre. 
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The diagram shows how three polypeptide chains make one collage molecule, and how many collagen molecules make collagen fibrils. 

Well done my friend! Onwards we go! 🙌

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Written by Aayushi | GCE CIE Biology Specialist @ TUTTEE

  References:

  • Cornell, B. Fibrous vs Globular Proteins. Retrieved from https://ib.bioninja.com.au/standard-level/topic-2-molecular-biology/24-proteins/fibrous-vs-globular-protein.html 
  • Jones, M., & Parkin, M. (2018). Cambridge International AS and A Level Biology. Cambridge: Cambridge University Press.  
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