IBDP Biology Question Analysis Topic: Biology - Short Questions
1) How have transgenic animals proved to be beneficial in the following application of transgenic?
(a) Production of biological products
(b) Chemical safety testing
2) Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally?
1) (a) Rosie, a transgenic cow that produces enhanced milk with alpha lactalbumin, human protein, and alpha I anti-trypsin for the treatment of emphysema.
(b) Toxicology testing: Transgenic animals have genes that increase their sensitivity to toxins and speed up the process of getting results.
2) As alien DNA needs certain recognition sequences in order to ligate to the host chromosome, it cannot join the chromosome anywhere along its length and reproduce normally. The sequence should also be near to the point at which DNA replication begins, known as Ori. The DNA polymerase must attach to this location in order to begin replication.
End of analysis. Great!