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AS/A-Level Chemistry - Formation of DNA

Formation of DNA

· A-level Chemistry,DNA,condensation polymer,biochemistry,deoxyribose

Let's learn about how the amazing DNA forms our life in A-Level Chemistry!

The formation

DNA forms by condensation polymerisation

The backbone of DNA is based on a repeated pattern of a sugar group and a phosphate group. 

The full name of DNA, deoxyribonucleic acid, gives you the name of the sugar present - deoxyribose.Deoxyribose is a modified form of another sugar called ribose. Ribose is the sugar in the backbone of RNA, ribonucleic acid.

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The sugar phosphate backbone is formed by condensation polymerisation. The lone pairs of electrons on an oxygen atom in the deoxyribose sugar molecule makes a dative covalent bond with the phosphorous atom in a phosphate group.

A molecule of water is lost and a phosphate-ester link is formed. There are still OH groups in the phosphate-ester, so further ester links can be formed.

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It is also a condensation reaction that connects base molecules to sugars in the sugar-phosphate backbone.

All of the bases have an NH group in their structure.

It’s the N atom of the NH group that bonds to deoxyribose –eliminating an OH group from the sugar and H from the NH to form water.

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Drafted by Eunice (Chemistry)

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AS/A-Level Chemistry - Structure of DNA
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I/GCSE Chemistry- Acids and Bases
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