GCSE Chemistry Question Analysis Topic: Chemistry - Proteins
Exam Question:
(a) Define the following terms related to proteins:
(i) Peptide linkage
(ii) Primary structure
(iii) Denaturation
Answer:
For GCSE Chemistry, you should know:
(i) Peptide linkage:
A covalent chemical bond known as a peptide bond (amide bond) connects two subsequent amino acid monomers along a peptide chain.
(ii) Primary structure:
The linear sequence of amino acids throughout the polypeptide chain is referred to as a protein's primary structure. Covalent bonds, such as peptide bonds, which are created during the process of protein biosynthesis, hold the primary structure together.
(iii) Denaturation:
By applying an external stressor, such as a strong acid or base, concentrated inorganic salt, an organic solvent (e.g. chloroform, alcohol), radiation, or heat: proteins and nucleic acids lose the quaternary structure, tertiary structure, and secondary structure that are present in their native state. Such a process is called denaturation.
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